Fatima Zahra Alaoui
HassanII University, Morocco
Biography
Fatima Zahra Alaoui specialist of internal medicine University hospital Ibn Rochd Casablanca Morocco Head of department of medicine in 2013-2017 Professor of internal medicine since 2007 Fields : auto-immune diseases , uveitis , Behcet disease , vascularisation , rheumatological inflammatory diseases Member of international society of Behcet disease.
Abstract
Background: Behcet’s disease (BD) is a chronic systemic inflammatory disorder of unknown etiology. It’s characterized by recurrent oral aphtosis and genital ulcer. Ocular involvement has been recognized since the time of Hypocrates. Estamates of the prevalence vary in different countries and may represent differences in the disease, in access to health care and in availabale treatments.
Aim: The aim of this study is to describe the epidemiological and clinical characteristics in Moroccan patients with ocular BD.
Methods: It’s a monocentric study, realized in an internal medicine department over 13 years and including 221 patients with ocular BD. The diagnosis was performed by the International Study Group for BD and/or the Davatchi Criteria for BD.
Results: 221 patients had ocular involvement and the prevalence was estimated at 43%. It was 158 men and 63 women (sex ratio M/F: 2:5). The mean age at the onset of ocular involvement was 30.5 years. This reached was inaugural in 18.55 % of cases and the average time of diagnosis in other cases was 3,41 years. The ocular involvement was serious from the start in the half-patients and visual acuity was less than 5/10 in 71.56% of affected eyes.
There was a high prevalence of uveitis: 97%
Conclusion: Up to 70% of patients with the BD will get eye involvement and current estimates from around the world indicate that severe visual impairment occurs in 25 % of involved eyes. Accordingly, the early detection and appropriate treatment of this reached is vital to preserve visual function of our patients.